aerobe ae·robe UK/ˈɛː.rəʊb/ US/ˈɛˌroʊb/ uncommon noun 1. an organism especially a bacterium that requires air or free oxygen for life Related words Broader terms organism WordNet 2.1 (Princeton University). Wiktionary (CC BY-SA). CMU Pronouncing Dictionary. WordNet 2.1 Copyright Princeton University. All rights reserved.