PPP uncommon slang uk us noun 1. surgical resection of unnecessary palatal and oropharyngeal tissue to open the airway; intended to cure extreme cases of snoring (with or without sleep apnea) SynonymspalatopharyngoplastyuvulopalatopharyngoplastyUPPP Related words Broader terms operation WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.