SLS uncommon noun 1. a caustic detergent useful for removing grease; although commonly included in personal care items (shampoos and toothpastes etc.) it can irritate skin and should not be swallowed Synonymssodium lauryl sulphatesodium lauryl sulfate Related words Broader terms sulfatedetergent WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.