two-handed two·han·ded uncommon adjective 1. equally skillful with each hand “an ambidextrous surgeon” Synonymsambidextrous Antonymsright-handedleft-handed Similarequipoised 2. requiring two hands or designed for two people “a two-handed sledgehammer” “a two-handed crosscut saw” “a machine designed for bimanual operation” Synonymsbimanual Similarhanded Related words Word family two-handed backhandtwo-handed saw WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.