Vizcaino viz·caino US/vizkɑˈinoʊ/ uncommon noun 1. Spanish explorer who was the first European to explore the California coast (1550-1615) SynonymsSebastian Vizcaino Related words Broader terms explorer WordNet 2.1 (Princeton University). CMU Pronouncing Dictionary. WordNet 2.1 Copyright Princeton University. All rights reserved.