Up to now, scientists have discovered that the human proteome is significantly more complex than the human genome. While the genome comprises 20,000-25,000 genes, the proteome is estimated over 1 million proteins.

SILAC-based quantitative proteomics (SILAQ) is an innovative technology used in high throughput quantitative analysis of large protein complexes, protein-protein and protein-small molecule interactions.

Shotgun proteomics refers to a use of bottom-up proteomics techniques to study the whole proteins in a complex mixture, such as serum, urine, and cell lysates, etc. It utilizes the technology of high performance liquid chromatography.

The transfer of one-carbon methyl groups to nitrogen or oxygen (N- and O-methylation, respectively) to amino acid side chains increases the hydrophobicity of the protein and can neutralize a negative amino acid charge when bound to carboxylic acids.

Ubiquitin is an about 8.5 kDa polypeptide consisting of 76 amino acids that is appended to the ?-NH2 of lysine in target proteins via the C-terminal glycine of ubiquitin.

If an exact knowledge of protein/peptide quantities is required for further applications, quantitative amino acid analysis, qAAA, is a suitable assay, which can not only determine protein quantities precisely.

Creative Proteomics is the proteomics division of Creative Dynamics Inc, an integrated CRO company that provides a full range of drug development services, including Molecular Biology.

Creative Proteomics offers iTRAQ protein quantification service suited for unbiased untargeted biomarker discovery.

Stapled peptide is a full-carbon scaffold with an ?-helical structure. The all-carbon scaffold stabilizes the ?-helical structure, enhances the interaction between the peptide molecule and the protein, and the peptide can pass through the cell membra

Various labeling techniques are developed in BOC Sciences such as enzymatic labeling, protein labeling, genetic labeling and quantum dot are widely utilized to meet our customers' need. Just contact [email protected] for more information.

The protein quantification is based on isotope dilution LC-MS/MS and Multiple Reaction Monitoring (MRM) of specific peptides from the protein(s) of interest. More information: [email protected] Tel:5166698109