The bioavailability of buy UK branded zopiclone, i.e. the amount of drug available in the circulation after the drug is taken orally, is 75- 80%. This means that the drug is very effective when taken orally. Zopiclone gets widely distributed in all the tissues including the brain. It reaches the maximum plasma concentration in 1-2 hours and the drug starts acting quite fast. It is metabolized by the liver and excreted in the urine.