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Akt, or protein kinase B (PKB), is a Ser/Thr protein kinase that phosphorylates a variety of protein substrates to regulate numerous cellular functions. Such as protein synthesis, metabolism, transcription, cellular proliferation, cellular differenti

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KIR, short for Killer-cell Immunoglobulin-like Receptor, is a receptor mainly expressed on the surface of natural killer (NK) cells and some T cells, which can recognize the major histocompatibility complex class I ?MHC-I? on the surface of target.

cell immunoglobulin and mucin domain 3 (TIM3) is a member of Tim family, which consists of 301 amino acids. The common structure of TIM3 molecules includes: variable region of N-terminal immunoglobulin, mucin domain, transmembrane region and intracel

T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a type 1 transmembrane protein containing an IgV extracellular domain and an immunoglobulin tail tyrosine (ITT)-like phosphorylation motif followed by an immunoreceptor tyrosine-based inhibito

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Centromere-associated protein E (CENP-E) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centromere-associated proteins, it is not present during interphase and first appears at the centromere region.