Creative Biostructure is specialized in plasmid construction of full-length, site-mutated, truncated and tagged proteins. The constructed gene is cloned into a suitable vector and expressed in an appropriate cell line.

HCT116 is a human colorectal carcinoma cell line initiated from an adult male. The cells are adherent with an epithelial morphology. Following implantation into immunocompromised mice, the cells form primary tumors and distant metastases.

Cre lentiviral particle is a high titer (1x10^8) lentiviral particle, which can directly infect all mamaliam cells. Total volume is 50 microliter. Recombinase Cre is drived by CMV promoter.

Pharmacokinetics (PK) studies provide critical information regarding the behavior of a drug in circulation and its ultimate form after extensive in vivo metabolism.

Linkers facilities the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemica

Creative Biostructure has developed an advanced purification platform to provide protein samples with "crystallographic grade" purity (i.e., >95%) and ready for crystallization and other high quality assays.

Jurkat cell line was established from the peripheral blood of a 14-year-old boy with acute lymphoblastic leukemia (ALL) at first relapse in 1976; often this cell line is called "JM" (JURKAT and JM are derived from the same patient and are sister.

Cardiomyocytes are derived from the whole heart (of a single donor) that has been dissociated into single cells and cultured using differential adhesion.

We can provide a complete package or stand-alone services for biologics process development and analytical development services.

Thyroid cells are isolated from human thyroid tissue which can produce thyroid hormones. As an endocrine gland, thyroid plays an important role in metabolism regulation and growing development.

Lanoptik is a China-based company specializes in microscope camera and microscope software.

The protein quantification is based on isotope dilution LC-MS/MS and Multiple Reaction Monitoring (MRM) of specific peptides from the protein(s) of interest. More information: [email protected] Tel:5166698109

Ipatasertib, also known as GDC-0068, is a strong ATP-competitive pan-AKT inhibitor. It was initially derived during the screening and optimization process of a series of 6,7-dihydro-5H-cyclopenta[d]pyrimidine compounds.

Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured.

In enzymology, a pyruvate oxidase (EC 1.2.3.3) is an enzyme that catalyzes the chemical reaction: pyruvate + phosphate + O2 ? acetyl phosphate + CO2 + H2O2. The 3 substrates of this enzyme are pyruvate, phosphate, and O2.

Cysteine residues serve essential roles in protein structure and function due to their highly reactive thiol side chains that form inter or intra molecular di-sulfide bonds to enable correct protein folding. Thiol reactivity also provides an appealin

HThF from Creative Bioarray are isolated from human thyroid tissue. HThF are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume.

Our novel Chimeric Antigen Receptor (CAR) technology platform consists of several key services including CAR construction, pseudoviral particles production and stable transduction.

Cell systems are used as tools and models for basic research and industrial applications over the last few decades. These cell systems rely on the use of cell lines.

KAI-1678 is an inhibitor of epsilon protein kinase C in the treatment of neuropathic pain in patients with PHN. It could be used for Postherpetic neuralgia (PHN); Postoperative pain; Spinal cord injury; Neuropathic pain.

Established from the bone marrow of a 31-year-old woman with acute myeloid leukemia (AML FAB M5a) at 2nd relapse; described to show strong lysozyme activity in the cytoplasm, phagocytic activities.

PetrographypediA is a portal of petrography. It provides an interactive atlas of thin-section photomicrograph analyses. It helps the process of petrographic description and analysis.

Human Primary Pancreatic Fibroblasts are isolated from normal human pancreatic tissue.

Biologics Process Development provides contact laboratory services for biotechnology industry. It offers biology, cell culture, bacterial fermentation, recombinant protein purification and expression, cold and frozen cell/material storage.

Ubiquitin is an about 8.5 kDa polypeptide consisting of 76 amino acids that is appended to the ?-NH2 of lysine in target proteins via the C-terminal glycine of ubiquitin.

Viral testing and clearance is an essential quality control procedure in manufacture process of drug and clinic products. Virus contamination is a terrible problem for which may cause bad effects on body, even severe illness.

Linker design for ADCs is highly dependent on the biolology of the target cells, the characteristics of the antibody, and the structure of the drug molecule. Selection of the optimal linker is achieved through efficacy and toxicity assessments for ea

Tyrosinase (TYR) is the key enzyme regulating melanin production in hair and skin in humans. Although melanin displays maximal optical absorption at ultraviolet wavelengths, melanin has a broad spectrum of optical absorption with significant absorpti

Creative Biolabs' strong expertise in construction of library allows it to construct complex thioredoxin (TrxA) libraries without any dramatic increase in cost.

Nanotize Solutions uses innovative and environmentally responsible molecular technologies to disinfect, sanitize, and protect any surface to meet society's growing sanitation demands. With an array of patented next-generation products, Nanotize Solutions provides durable surface protection that prevents microbial growth for all industries.