central nervous system cent·ral·ner·voussystem uncommon noun 1. the portion of the vertebrate nervous system consisting of the brain and spinal cord Synonymscentral nervous systemCNSsystema nervosum centrale Related words Broader terms system Parts nervous system Part of neurogliabrainpyramidal tractspinal cordwhite matter WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.