family Endamoebidae fa·mi·lyen·damoebidae uncommon noun 1. a large family of endoparasitic amebas that invade the digestive tract SynonymsEndamoebidaefamily Endamoebidae Related words Broader terms family Parts Amoebida Part of Endamoeba WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.