horse-pistol hor·se·pis·tol uncommon noun 1. a large pistol (usually in a holster) formerly carried by horsemen Synonymshorse pistol 2. a large pistol (usually in a holster) formerly carried by horsemen Synonymshorse pistolhorse-pistol Related words Word family horse-pistol Broader terms pistol WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.