Hypericum pyramidatum hy·pe·ri·cumpyramidatum uncommon noun 1. perennial shrub having large star-shaped yellow flowers in narrowly pyramidal cymes Synonymsgreat St John's wortHypericum ascyronHypericum pyramidatum Related words Broader terms St John's wort WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.