misanthropical mi·santh·ro·pical uncommon adjective 1. believing the worst of human nature and motives; having a sneering disbelief in e.g. selflessness of others Synonymscynicalmisanthropic Similardistrustful 2. hating mankind in general Synonymsmisanthropic Similarill-natured WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.