Mithridates VI mith·ri·da·tesvi uncommon noun 1. ancient king of Pontus who expanded his kingdom by defeating the Romans but was later driven out by Pompey (132-63 BC) SynonymsMithridatesMithridates VIMithridates the Great Related words Broader terms king WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.