mitral valve mit·ral·valve uncommon noun 1. valve with two cusps; situated between the left atrium and the left ventricle Synonymsmitral valvebicuspid valveleft atrioventricular valve Related words Word family mitral valve prolapsemitral valve stenosis Broader terms atrioventricular valve WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.