pilar cyst pi·lar·cyst uncommon noun 1. a common cyst of the skin; filled with fatty matter (sebum) that is secreted by a sebaceous gland that has been blocked Synonymssebaceous cystpilar cystwensteatocystoma Related words Broader terms cyst Narrower terms chalazion WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.