psychoactive substance psyc·hoac·ti·vesubstance uncommon noun 1. a drug that can produce mood changes and distorted perceptions Synonymspsychoactive drugmind-altering drugconsciousness-altering drugpsychoactive substance Related words Broader terms drug Narrower terms designer drugdronabinoleuphorianthallucinogentetrahydrocannabinol WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.
