Saint James the Apostle saint·ja·mest·heapostle uncommon noun 1. (New Testament) disciple of Jesus; brother of John; author of the Epistle of James in the New Testament SynonymsJamesSaint JamesSt. JamesSaint James the ApostleSt. James the Apostle Related words Broader terms Apostlesaint WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.