Santa Ana san·taana uncommon noun 1. a strong hot dry wind that blows in winter from the deserts of southern California toward the Pacific Coast SynonymsSanta Ana 2. Mexican general who tried to crush the Texas revolt and who lost battles to Winfield Scott and Zachary Taylor in the Mexican War (1795-1876) SynonymsSanta AnnaSanta AnaAntonio Lopez de Santa AnnaAntonio Lopez de Santa Ana 3. a city in southern California east of Long Beach SynonymsSanta Ana 4. a city in western El Salvador SynonymsSanta Ana Related words Broader terms citygeneralwind Parts El SalvadorCalifornia WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.