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PD-1/PD-L1 inhibitors pharmacologically preventing the PD-1/PD-L1 interaction may provide a potential way to facilitate immune response to kill the tumor. There are quite PD-1 inhibitors in clinical trials as well as available in the market approved
Acetyl Dipeptide-3 Aminohexanoate reinforces the skin's innate immunity by stimulating the first line of defense between the skin and the environment. It can effectively lower the risk of possible infections by external agents in acne-prone skin.
Difelikefalin ,also known as D-Phe-D-Phe-D-Leu-D-Lys-[?-(4-N-piperidinyl)amino carboxylic acid] (as the acetate salt), is an analgesic opioid peptide acting as a peripherally specific, highly selective agonist of the ?-opioid receptor (KOR).
Beta-Amyloid Fragments now can be reached at Creative Peptides.
Peptide drug refers to a peptide having a specific therapeutic effect extracted by chemical synthesis, genetic recombination or animal or plant, and is a specific application of the peptide in the field of medicine. The biological activity of the pep
Acetyl Tetrapeptide-9 palys a role in the stimulation of basement membrane polysaccharide (lumican) and the synthesis of collagen I. Acetyl Tetrapeptide-9 promote dermal remodeling and helps achieve compact and plump the skin effect.
Dipeptide-15 is the synthetic peptide consisting of glycine.
Delcasertib,a Novel ?-Protein Kinase C Inhibitor,is composed of a selective ?-protein kinase C (?PKC) inhibitor peptide conjugated reversibly to the cell-penetrating peptide via a disulfide bond.
The C-terminal of the peptide is synthesized as an amide to neutralize negative charge created by the C-terminal COOH. This modification is added to prevent enzyme degradation, to mimic native proteins, and in some cases to remove hydrogen bonding.
The introduction of non-natural amino acids generates modifications in the secondary and tertiary structures of a peptide, and is used to further enhance the stability and activity of peptide sequences.
Peptide lead optimization is to improve upon a lead molecule that demonstrates activity at a target of interest by optimizing its potency or selectivity at the target and its absorption, distribution, metabolism and elimination (ADME) properties.
Hygromycin B is a fda approved antibiotic food additive for swine and poultry Hygromycin B is an antibiotic produced by the bacterium Streptomyces hygroscopicus. It is an aminoglycoside that kills bacteria, fungi and higher eukaryotic cells by inhibi
Stable isotope labeled peptides have been widely applied in the nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS). Creative Peptides can provide customized peptides labeled with stable isotopes including 2H, 15N & 13C
Amylins Fragment can be obtained at Creative Peptides, a professional peptide supplier founded a decade ago. For more, contact [email protected]
GLP-1 is a naturally-occurring peptide that is released within minutes of eating a meal. It is known to suppress glucagon secretion from pancreatic alpha cells and stimulate insulin secretion by pancreatic beta cells. GLP-1 receptor agonists are in d
Antistine-Privine (Antazoline Sulfate) is a 1st generation antihistamine, with good anticholinergic properties. It is used to relieve nasal congestion and added in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergi
The following suggestions should be considered in the design of a peptide. They also determine the solubility of the final product.
Reduce the length of sequence
Reduce the number of hydrophobic residues
Reduce difficult residues
Change the seq
Creative Peptides provides a one-stop solution for all of your peptide-drug bioconjugation needs. Our custom peptide synthesis, modification, and conjugation services involve chemical modification of peptide at highly specific sites.
Notably, peptoids lack the amide hydrogen which is responsible for many of the secondary structure elements in peptides and proteins. Peptoids were first invented by Reyna J. Simon, Paul Bartlett and Daniel V. Santi to mimic protein/peptide products.
Creative Peptides can provide bioactivities peptides which have been proven in their efficacy through clinical skin trials. A number of peptides possess the capability of anti-aging. Among them the most popular peptides is Acetyl hexapeptide-3.
Checkpoint Inhibitors
Cat. # Product Name
CR00002 HIV-1 gag Protein p17 (76-84)
CR00001 CBP501 Affinity Peptide.
More at [email protected]
Antimicrobial peptides (AMPs), also called host defense peptides (HDPs), which commonly content 5-40 amino acids, are natural antibiotics produced by various organisms. The first AMP was found by Dubos when extracted an antimicrobial agent from a soi
Myristoyl Hexapeptide-23 is a synthetic peptide consisting of alanine, leucine and lysine residues. Myristoyl Hexapeptide-23 is a new lipid oligopeptide with anti-acne efficacy.
Fibronectin Fragments / RGD Peptides
Cat. # Product Name
CR00006 RGD-4C
CR00005 E[c(RGDfK)]c(RGDfK)
CR00004 FITC-?Ahx-Gly-Arg-Gly-Asp-Ser-Pro-OH.
More at info@creative-peptide
On the basis of extensive experience in peptide synthesis, Creative Peptides proudly offers the most comprehensive glycopeptides synthesis services to our worldwide clients. Our scientists are committed to deliver high quality glycopeptides which wil
Creative Peptides specializes in the development and GMP manufacture of pharmaceutical grade peptides.A wide range of uses of GMP peptides:
In vitro diagnostics
Biopharmaceutical
QC controls and standards
Pre-clinical studies.
Creative Peptides can offer off-the-shelf tumor antigen peptides that can be used for antigen stimulation research by our clients. We especially provide customized GMP grade tumor antigen peptides with competitive price.
Creative Peptides provides custom conjugation of various peptides, full length antibody, enzymes and other proteins to our gold nanoparticles (AuNPs) or silver nanoparticles (AgNPs) with a wide range of available size (up to 100nm in diameter).
Acetyl Hexapeptide-1 is the reaction product of Alanine, arginine, histidine, leucine, phenylalanine and tryptophane hexapeptide with acetic acid. It activates the regulation of melanin synthesis, relating the protection of natural light and inflamm
n recent years, with the development of biotechnology and the introduction of oligopeptide absorption mechanism, the research on oligopeptides has received more and more attention.
Creative Peptides is specialized in the peptide modification services, providing a confidential and efficient service at competitive prices. Every step of peptide synthesis is subject to Creative Peptides' stringent quality control.
Post-translational modifications (PTMs) are changes to proteins or peptides that are catalyzed by enzymes after completion of ribosomal translation and it generally have a positive impact on peptide activity.
Abaloparatide is a parathyroid hormone-related protein (PTHrP) analog drug in clinical development for treating osteoporosis. Like the related drug teriparatide, and unlike bisphosphonates, it is an anabolic (i.e., bone growing) agent.
In a study enrolling 39 Caucasian women, facial pigment spots significantly faded after 6 weeks when PKEK was combined with the skin whitener sodium ascorbyl phosphate (SAP).Creative Peptides is able to provide comprehensive support for our client.
Creative Peptides provides custom conjugation services include:
Fluorophore Conjugation Service
Biotinylation
Horseradish Peroxidase (HRP) Conjugation Service
Gold/Silver Nanoparticles Conjugation Service
Magnetic Beads Conjugatio
A wide range of FRET Substrates are now available at Creative Peptides. Just contact us [email protected] for more information.
? Secretase Inhibitors can be obtained at Creative Peptides, a professional peptide supplier founded a decade ago. For more, contact [email protected]
Liraglutide (NN2211) is a long-acting glucagon-like peptide-1 receptor agonist, binding to the same receptors as does the endogenous metabolic hormone GLP-1 that stimulates insulin secretion.
Acetyl Tetrapeptide-3 is product obtained by the acetylation of Tetrapeptide-3.
An intravenous infusion of oxytocin is used to induce labor and to support labor in case of slow childbirth.Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release.
With ten years experience in antigen peptides supply, Creative Peptides is experienced in the synthesis of complex antigen peptides, such as glycopeptides or hyperphosphorylation peptides.
Dalbavancin is a semisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides currently available, vancomycin and teicoplanin. It possesses in vitro activity against a variety of Gram-positive pathogens including MRSA.
A wide range of A wide range of A wide range of Tau Fragments are now available at Creative Peptides. Just contact us [email protected] for more information.
Creative Peptides has extensively developed stapled peptide structures and is the company of choice to manufacture your stapled peptide requirements, providing a confidential and efficient service at competitive prices.
Myristoyl Pentapeptide-16 is a synthetic peptide containing leucine, lysine and serine residues.
There are some challenges to the synthesis of long peptides, such as a large cumulative effect of yield, which can result in slow or incomplete coupling and/or reverse protection during the synthesis, as well as low solubility in the assembly.
Gastric Inhibitory Polypeptide and Fragments
Cat. # Product Name Price
AF2506 Gastric inhibitory polypeptide
G02012 Gastric Inhibitory Polypeptide (porcine)
G02002 Gastric Inhibitory Polypeptide (6-30) amide (human).
More at info@creative-pe
Cat. # Product Name Price
M3001 Z-Pro-Leu-Gly-NHOH Inquiry
M3006 Z-Pro-Leu-Ala-NHOH Inquiry
M3007 Z-Pro-D-Leu-D-Ala-NHOH Inquiry
M3004 Peptide 74 Inquiry
M3117 Mca-(Ala7,Lys(Dnp)9)-Bradykinin Inquiry
Stapled peptide is a full-carbon scaffold with an ?-helical structure. The all-carbon scaffold stabilizes the ?-helical structure, enhances the interaction between the peptide molecule and the protein, and the peptide can pass through the cell membra
Myristoyl Pentapeptide-17 is the reaction product of myristic acid and Pentapeptide-17. It promotes the delivery of key ingredients for quicker lash growth, thus stimulates the hair growth at the follicle.
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