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cell knockout

Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications.

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Custom peptide synthesis

In the quantitative proteomics research, several MS-based methodologies for relative quantification have been introduced for comparison of different proteomes from collected biological samples.

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Human cardiomyocytes

Cardiomyocytes are derived from the whole heart (of a single donor) that has been dissociated into single cells and cultured using differential adhesion.

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Protein Ptm Analysis

Up to now, scientists have discovered that the human proteome is significantly more complex than the human genome.

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opls-da

Orthogonal partial least squares discriminant analysis (OPLS-DA) was introduced as an improvement of the PLS-DA approach to discriminate two or more groups (classes).

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Human Oral Primary Cells

Oral cells are isolated from human oral tissues such as tongue, oral mucosa, periodontal tissue, and so on. The mouth is one of the most important organ because it is the site of food intake.

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itraq protein quantification service

Creative Proteomics offers iTRAQ protein quantification service suited for unbiased untargeted biomarker discovery.

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Protein quantification

Creative Proteomics is the proteomics division of Creative Dynamics Inc, an integrated CRO company that provides a full range of drug development services, including Molecular Biology.

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Human Hepatocytes

The liver fulfills many vital processes in mammals. It is the central organ of energy metabolism, biotransformation of xenobiotics, and synthesis of plasma proteins under physiological and pathophysiological conditions.

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Gc analysis services

Gas Chromatography (GC) is an analytical technique for a wide variety of volatile and/or semi-volatile organic compounds identification and quantitation. It is an indispensable technique for analytical lab to analysis a variety assortment sample type

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Protein identification by mass spectrometry

With the advancement in mass spectrometry technology, protein and peptide identification is no more tedious and time consuming.

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Catalase

Catalase is a common enzyme found in nearly all living organisms, where it functions to catalyze the decomposition of hydrogen peroxide to water and oxygen.

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lc mrm ms

The protein quantification is based on isotope dilution LC-MS/MS and Multiple Reaction Monitoring (MRM) of specific peptides from the protein(s) of interest. More information: contact@creative-proteomics.com Tel:5166698109

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hcc-78

Established from the pleural effusion of a 65-year-old man with adenocarcinoma of the lung, typed as non-small cell lung carcinoma; matched EBV+ B-lymphoblastoid cell line (B-LCL) is available (HCC-78BL)

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Human placenta primary cells

Placental Epithelial Cells are of fetal origin and form a single layer at the inner surface of the amnion. They protect the fetus against maternal leukocytes, neoplastic cells, and pathogens.

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Chymotrypsinogen a

Chymotrypsinogen is a proteolytic enzyme and a precursor (zymogen) of the digestive enzyme chymotrypsin. It is a single polypetide chain consisting of 245 amino acid residues. More information contact@creative-enzymes.com Tel:5166698109

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Human pancreatic cells

Human Primary Pancreatic Fibroblasts are isolated from normal human pancreatic tissue.

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Carbonic Anhydrase

The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa).

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2-d electrophoresis

Creative Proteomics offers an integrated solution for the identification of low abundance proteins in complex biological sample through 2D electrophoresis. More information: contact@creative-proteomics.com Tel:5166698109

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lentiviral vector

Creative Biogene offers Premade Lentivirus Particles for your research, please inquiry online. More information: contact@creative-biogene.com Tel:5166698109

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Nuclease S1

Nuclease S1 isolated from Aspergillus oryzae exhibits endo-and exolytic hydrolytic activity for the phosphodiester bonds of single-stranded DNA and RNA yielding 5’-phosphomononucleotide and 5’-phosphooligonucleotide end-products.

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Creatinine hydrolase

Creatinine Amidohydrolase catalyzes the hydrolytic reaction converting creatinine to creatine. The enzyme is purified from a microorganism. More information: contact@creative-enzymes.com Tel:5166698109

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Human Bone Primary Cells

Bone cells, which are found within the bone tissue, are responsible for bone production, maintenance and modeling. There are three different types of cells that found only in the bone.

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Quantitative amino acid analysis

If an exact knowledge of protein/peptide quantities is required for further applications, quantitative amino acid analysis, qAAA, is a suitable assay, which can not only determine protein quantities precisely.

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Shotgun proteomic analysis

Shotgun proteomics refers to a use of bottom-up proteomics techniques to study the whole proteins in a complex mixture, such as serum, urine, and cell lysates, etc. It utilizes the technology of high performance liquid chromatography.

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Post-translational modification

Up to now, scientists have discovered that the human proteome is significantly more complex than the human genome.

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Peptide de novo sequencing

De novo protein sequencing is a process by which the amino acid sequence is deduced without prior knowledge of the DNA or protein sequence.

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MicroRNA (miRNA)

reative Biogene provides world-class MicroRNA (miRNA) sponge service and we have been perfecting MicroRNA sponge service for many years.

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Aqua Proteomics

Absolute Quantification is a targeted quantitative proteomics technique that exhibits robust efficacy and is being increasingly utilized for a wide variety of quantitative proteomics studies.

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Itraq protein quantification service

Creative Proteomics offers iTRAQ protein quantification service suited for unbiased untargeted biomarker discovery.

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Protein methylation

The transfer of one-carbon methyl groups to nitrogen or oxygen (N- and O-methylation, respectively) to amino acid side chains increases the hydrophobicity of the protein and can neutralize a negative amino acid charge when bound to carboxylic acids.

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post translational modification ubiquitination

Ubiquitin is an about 8.5 kDa polypeptide consisting of 76 amino acids that is appended to the ?-NH2 of lysine in target proteins via the C-terminal glycine of ubiquitin.

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Protein Phosphorylation

Glycosylation, the connection of sugar moieties to proteins, is a post-translational change (PTM) that gives more prominent proteomic differences than different PTMs. Glycosylation is basic for an extensive variety of natural procedures.

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Peptide mass fingerprinting for protein identification

Peptide mass fingerprinting (PMF) is an analytical technique for protein identification. Basically, the unknown protein of interest is first cleaved into smaller peptides, whose absolute masses can be accurately measured with a mass spectrometer.

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TEX35 Full-Length MS Protein Standard

C1orf49 Full-Length MS Protein Standard (NP_115502), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency a

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silac quantitative proteomics

SILAC-based quantitative proteomics (SILAQ) is an innovative technology used in high throughput quantitative analysis of large protein complexes, protein-protein and protein-small molecule interactions.

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Human Esophagus Cells

The esophagus is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx to the stomach.

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Peptide Mass Fingerprinting analysis

Innovative Proteomics gives Peptide Mass Fingerprinting (PMF) investigation and particles scanning against database for fast recognizable proof of proteins.

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Gas chromatography

Gas Chromatography (GC) is an analytical technique for a wide variety of volatile and/or semi-volatile organic compounds identification and quantitation. It is an indispensable technique for analytical lab to analysis a variety assortment sample type

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Mass spectrometry based lipidomics

Lipids are hydrophobic or amphipathic small molecules which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides and phospholipids.

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Post translational modification glycosylation

Glycosylation, the attachment of sugar moieties to proteins, is a post-translational modification (PTM) that provides greater proteomic diversity than other PTMs.

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Cal-51

Set up from the pleural emission metastasis of a 45-year-old lady with dynamic bosom adenocarcinoma (after radio-, chemotherapy and surgery) in 1985; uncommon case of tumor cell line with ordinary karyotype.

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Glycan Analysis

Glycan functions are usually determined by the structures of the oligosaccharides, which are covalently attached to proteins primarily at 2 structural motifs.

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Customized Synthesized Peptide

For SIL peptides/proteins, the products from Creative Proteomics are not only highly pure, but also synthesized with high isotope incorporation, for excellent MS analysis. More information: contact@creative-proteomics.com Tel:5166698109

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Protein methylation

Methylation is a well-known mechanism of epigenetic regulation, as histone methylation and demethylation influences the availability of DNA for transcription.

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Bioinformatics for Proteomics

Proteins govern most biological processes and functions. Recently, much attention has been paid to study the entire protein sets available in a cell.

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Protein ubiquitination analysis

Ubiquitin is an about 8.5 kDa polypeptide consisting of 76 amino acids that is appended to the ?-NH2 of lysine in target proteins via the C-terminal glycine of ubiquitin.

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Human peripheral blood cells

Peripheral blood cells are the cellular components of blood, consisting of erythrocytes, leucocytes and platelets, which are found within the circulating pool of blood.

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Human thyroid cells

Thyroid cells are isolated from human thyroid tissue which can produce thyroid hormones. As an endocrine gland, thyroid plays an important role in metabolism regulation and growing development.

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acyl-CoA oxidase

In enzymology, an acyl-CoA oxidase (EC 1.3.3.6) is an enzyme that catalyzes the chemical reaction acyl-CoA + O2? trans-2, 3-dehydroacyl-CoA + H2O2.

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