RO4929097 - CAS 847925-91-1

RO4929097, a small-molecule inhibitor of ? secretase (IC50= 4 nM, EC50= 5 nM), inhibits cellular processing of A?40 (EC50= 14 nM) and Notch(EC50= 5 nM). In vitro: Decreases the amount of A? peptides secreted into the culture medium in HEK293 cells (E

Category: Science-technology > Biochemistry > Notch-signaling-pathway Upgrade Options