Helping to share the web since 1996
United States Free with your profile
Your free digital card
A live card with your name, a QR code and a wallet pass. It is ready from this profile, and printed cards follow when you want them in a pocket.
Contact
Get in touch
Contact
Alex Brown
Address
45-16 Ramsey Road Shirley, NY 11967, USA, Shirley, New York, 11967
United States
United States
Websites & Listings
50 listed websites
Hsp90 uses a host of cochaperones which not only regulate the ATPase activity and conformational dynamics but which also mediate interactions with Hsp90 client proteins.
Akt, or protein kinase B (PKB), is a Ser/Thr protein kinase that phosphorylates a variety of protein substrates to regulate numerous cellular functions. Such as protein synthesis, metabolism, transcription, cellular proliferation, cellular differenti
IDO inhibitors may help to promote an enhanced immune response against the tumor by blocking the IDO enzyme which reduces the depletion of tryptophan.
Nivolumab, marketed as Opdivo, is a humanized IgG4 anti-PD-1 monoclonal antibody used to treat cancer. Nivolumab works as a checkpoint inhibitor, blocking a signal that would have prevented activated T cells from attacking the cancer, thus allowing.
CTLA-4, short for Cytotoxic T-Lymphocyte-Associated protein 4 and also called CD152. The first immunecheckpoint receptor to be clinically targeted, is expressed exclusively on T cells where it primarily regulates the amplitude of the early stages.
Pilaralisib is a Class 1 phosphatidylinositol 3 kinase (PI3K) family inhibitor. It is an orally bioavailable small molecule, targeting the class I PI3K family of lipid kinases. It is a pyrimidine derivatives compound discovered by Exelixis Inc.
Duvelisib, also known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic acti
Scientists at BOC Sciences have written many articles about various signaling pathway.
PI3K (Phosphatidylinositol-4,5-bisphosphate 3-kinase) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.
BOC Sciences has directed sincere efforts toward providing customers with top quality products designed for optimum flavoring and smell.
For customers convenience, we classify products on the basis of olfactive family. Besides, you can enter CAS,
Herceptin (Trastuzumab) is a monoclonal antibody drug for the treatment of breast cancer which is HER2 receptor positive. It acts via binding to HER2 receptor to suppress cell duplication.
Dopamine Reuptake Inhibitors (DRIs) are drugs that function by preventing the reuptake of the neurotransmitter dopamine. The fact that they prevent dopamine reuptake leads to increased concentrations of dopamine between synapses.
Tofacitinib (CP-690550,Tasocitinib) is a novel inhibitor of JAK3 with IC50 of 1 nM, 20- to 100-fold less potent against JAK2 and JAK1.It is currently approved for the treatment of rheumatoid arthritis (RA) in the United States.
Dynamin is a GTPase responsible for endocytosis in the eukaryotic cell. Dynamins are principally involved in the scission of newly formed vesicles from the membrane of one cellular compartment and their targeting to, and fusion with, another compartm
Peficitinib, also known as ASP015K and JNJ-54781532, is a novel potent JAK inhibitor, which demonstrated potent efficacy in adjuvant-induced arthritis model in rats. ASP015K may have potential use in prevention of rejection in solid organ transplanta
Anastrozole is an aromatase inhibitor that acts via binding competitively to the hem group of the CYP unit of the enzyme thereby reducing estrogen biosynthesis in the periphery and the breast. Anastrozole has little or no effect on other steroid horm
Glutamate is an essential excitatory neurotransmitter regulating brain functions. Excitatory amino acid transporter (EAAT)-2 is one of the major glutamate transporters expressed predominantly in astroglial cells and is responsible for 90% of total gl
wo endothelin receptor subtypes have been isolated and identified, endothelin A receptor(ETA) and endothelin B receptor (ETB), and are members of the seven transmembrane rhodopsin-like G-protein coupled receptor family (GPCRA) which stimulate multipl
WAY-316606 is a small molecule inhibitors of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. Modulators of the Wnt pathway have been proposed as anabolic agents for the treatment of osteoporosis or other bone-r
Elastase is an enzyme that digests and degrades a number of proteins including elastin, an elastic substance in the lungs and some other organs that supports their structural framework. Elastase is specifically inhibited by alpha-1 antitrypsin.
Description: Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. Molecular Formula C9H15N5O
Molecular Weight 209.25
Eph receptors (Ephs, after erythropoietin-producing human hepatocellular receptors) are a group of receptors that are activated in response to binding with Eph receptor-interacting proteins (Ephrins).
Rapamycin is a mTOR inhibitor immunosuppressant and kinase inhibitor with both antifungal and antineoplastic properties. It selectively inhibits the transcriptional activation of cytokines.
Fatty acid amide hydrolase or FAAH (oleamide hydrolase, anandamide amidohydrolase) is a member of the serine hydrolase family of enzymes. FAAH is an integral membrane hydrolase with a single N-terminal transmembrane domain.
FLAP is necessary in synthesis of leukotriene, which are lipid mediators of inflammation that is involved in respiratory and cardiovascular diseases. FLAP functions as a membrane anchor for 5-lipooxygenase and as an amine acid-bind protein.
Cyclosporine A - CAS 59865-13-3
Catalog number: 59865-13-3 Category: APIs
Molecular Formula C62H111N11 O12
Molecular Weight 1202.61
COA Inquire
Teriparatidet is an effective anabolic (i.e., bone growing) agent used in the treatment of some forms of osteoporosis. It is also occasionally used off-label to speed fracture healing.
Bis[4-(dimethylamino)phenyl]-[4-(methylamino)phenyl]methanol is produced from degradation of methyl green.
1,2,3,4,5,6,7,8-Octahydro-1-[(4-methoxyphenyl)methyl]isoquinoline is a useful synthetic compound.
Linaclotide is a peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation.
Customers are also welcome to provide literature methods or their own synthetic routes in which all relevant information such as reaction time, solvent, temperature, analytic data, purification method, yield, etc. is detailed.
Mertansine, the cytotoxic component in antibody-drug conjugates, attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker or SMCC (4-(3-mercapto-2,5-dioxo-1 pyrrolidinylmethyl)-cyl
Tasimelteon (trade name Hetlioz) is a drug approved by the FDA solely for the treatment of non-24-hour sleepwake disorder (often designated as N24HSWD) in totally blind adults.
Prepared by the two natural products, oxidation and oximation, of an 80:20 ratio of milbemycin A3 and A,Milbemycin oxime is a semi-synthetic macrocyclic lactone.
BOC Sciences advanced capabilities in carbohydrate synthetic area, purification and identification has benefited our customers in academia, research institutions, biotechnology and pharmaceutical at all stages of R&D from basic research to clinical
Ecamsule protect the skin from sunburn and erythema. It causes serious eye damage, so please wear protective gloves/protective clothing/eye protection/face protection.
DNA encoded library (DEL) is a new screening platform commonly used to discover small-molecules that interfere with the activity of pharmaceutically relevant proteins. DNA-encoded chemical libraries are hybrid-type collections of combinatorial organi
Superparamagnetic iron oxide microbeads have broad applications in biomedicine, such as magnetic cell isolation and biomolecules purification, magnetic resonance imaging of diseased tissues, magnetic immunoassay, targeted delivery of drugs and antige
The two most common naturally occurring amino acids that are used to attach the linker drug to the antibody are cysteines and lysines.
mTOR functions as a serine/threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. mTOR also functions as a tyrosine protein kinase that promotes the acti
Histone deacetylases (HDACs), that may be called protein deacetylases (PDAC) as some of their targets are non-histone proteins, are a family of eleven zinc-dependent enzymes that have gained major interest as therapeutic targets, mainly in cancer res
RO4929097, a small-molecule inhibitor of ? secretase (IC50= 4 nM, EC50= 5 nM), inhibits cellular processing of A?40 (EC50= 14 nM) and Notch(EC50= 5 nM). In vitro: Decreases the amount of A? peptides secreted into the culture medium in HEK293 cells (E
We have lots of compounds in stock, and our existing libraries of building blocks alongside with our specialized expertise allow short cut access to any desired novel nucleotide structure. In short, we are convinced that our custom nucleotides synthe
BOC Sciences is a leading biotechnology company which has years of professional and abundant experience in providing nucleoside synthesis service for customers all over the world. We can provide a large variety of synthesis scales, modifications serv
Apoptosis refers to the autonomous, orderly programmed cell death of cells controlled by genes to maintain homeostasis, and plays an important role in maintaining intracellular homeostasis. There are three main apoptotic pathways.
IL-1 is a cytokine produced by activated macrophages which mediates several physiological responses to infections and injuries, including stimulation of thymocyte proliferation, B-lymphocyte maturation and proliferation, induction of acute-phase prot
B lymphocytes can directly participate in humoral immune responses as immune effector cells, and can also be used as antigen-presenting cells to capture antigens and present them to T lymphocytes. B cells mediate foreign antigen signals and complex b
The human CTLA4 gene is located in the long arm 33 band of chromosome 2 and contains four exons encoding the leader sequence, the ligand binding region, the transmembrane region, and the cytoplasmic tail region, respectively. CTLA4 has two subtypes.
The active form of AMPK, i.e. phosphorylated AMP-activated protein kinase (p-AMPK), can down regulate the energy consuming process as well as increase adenosine triphosphate (ATP) generation through stimulating ATP-producing catabolic pathways.
Epidermal growth factor (EGF) was first discovered in newborn rats in 1962. After about 20 years, the human epidermal growth factor receptor (EGFR) was isolated and purified. As research progresses, EGFR and its downstream pathways are constantly und
Want a profile like this for your business?
Join 1M+ businesses on LinkCentre - list yours free in under 2 minutes.
List Your Business Free
Already own this listing? Claim this page