Indian tobacco in·dian·to·bacco uncommon noun 1. tobacco plant of South America and Mexico Synonymswild tobaccoIndian tobaccoNicotiana rustica 2. North American wild lobelia having small blue flowers and inflated capsules formerly used as an antispasmodic SynonymsIndian tobaccobladderpodLobelia inflata Related words Broader terms lobeliatobacco WordNet 2.1 (Princeton University). WordNet 2.1 Copyright Princeton University. All rights reserved.